MAF 878 Probiotic starter Macrocyte activating factor was researched by Dr. Yamamoto to supplement the immune system.
Normal Gc protein (also called Vitamin-D binding protein), an abundant glyco-protein found in human blood serum, it becomes a molecular switch to activate macrophages when it is converted to its active form, Gc macrophage activating factor (Gc-MAF). Gc protein is normally activated by conversion to Gc-MAF with the help of the B and T cells (bone marrow-made and thymus gland-made white blood cells) in the immune system. But, as researchers explain certain viruses cause a secretion of an enzyme known as alpha-N-acetylgalactosaminidase (also called Nagalase) that completely blocks conversion of Gc protein to Gc-MAF, preventing action by the macrophages. This is the way there is disengagement of the immune system, which may leave patients prone to infections or immune system symptoms. Originally the GcMAF was given by a once-weekly injection of minute amounts of Gc-MAF, just 100 nanograms (billionths of a gram), activates macrophages.
Nobuto Yamamoto, director of the Division of Cancer Immunology and Molecular Biology, Socrates Institute for Therapeutic Immunology, Philadelphia, Pennsylvania, says this is "probably the most potent macrophage activating factor ever discovered."
Once a sufficient number of activated macrophages are produced, another Gc-MAF injection is not needed for a week because macrophages have a half-life of about six days. After 16-22 weeks Nagalase enzyme reportedly fell to levels found in healthy people. It is not mandatory to measure Nagalase levels, the lab results received were insufficiently quality controlled. NK cells are a better indication.
Preparing MAF Starter Liquid
The starter contains probiotic bacteria and colostrum, which when added to kefir and yogurt will produce MAF.
Get a gallon glass jar; wide mouth jar is preferable, so that stirring is made easier. Wash the jar thoroughly, finally rinsing any soap residue.
*add container of starter to glass jar
*add one quart kefir to glass jar (goat kefir if lactose intolerant)
*add one quart yogurt to glass jar (goat yogurt if lactose intolerant)
*add one pint whole milk to glass jar (goat milk if lactose intolerant). The goat substitution may or may not satisfy the lactose intolerance, it varies patient to patient.
The final mixture is approx. 90 ounces (approx. 2 liters) sufficient for one month.
Stir thoroughly with new wooden spoon to mix starter throughout mixture. Keep this spoon solely for MAF.
Allow glass jar mixture to mature at room temperature for 5 days, stirring each day.
After five days the mixture should be ready for consumption and may be kept in a refrigerator.
Take 3 oz. (approx. 90ml) with food daily. You should have a salad with one teaspoon of olive oil or flax seed oil to reduce the gastric enzymes digesting the MAF 878.